What is hassalls corpuscle?

Hassall's corpuscles, also known as thymic corpuscles or corpuscles of Hassall, are small spherical structures found in the medulla of the thymus gland. They were first described by Arthur Hill Hassall in 1846.

Hassall's corpuscles are composed of epithelial cells arranged in concentric layers around a central cavity. The cells in the center of the corpuscle are degenerated and contain keratinized material. The size and number of Hassall's corpuscles vary depending on age and thymic function.

The function of Hassall's corpuscles is not fully understood, but they are believed to play a role in the development and maintenance of T lymphocytes, which are important cells in the immune system. Additionally, abnormal or absent Hassall's corpuscles can be indicative of certain diseases, including autoimmune disorders and immunodeficiencies.